Spinal shot vs IV drip: which helps you recover faster from robotic surgery?

NCT ID NCT06349668

Symptom relief Sponsor: Hans Bahlmann Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 3 trial tests whether a single spinal injection of morphine and bupivacaine before robotic kidney or ureter surgery leads to better recovery than an intravenous lidocaine drip during surgery. About 220 adults scheduled for robotic upper urinary tract surgery will be randomly assigned to one of the two pain management methods. The main goal is to see if the spinal group reports less drop in wellbeing the day after surgery, measured by a standard recovery questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: spinal morphine with bupivacaine
What this could lead to: If spinal morphine works better, it could become a standard way to improve recovery and reduce pain after robotic kidney or ureter surgery.
What could go wrong: This is a mid-stage trial with 220 participants, so results may not apply to everyone. Spinal morphine can cause itching, low blood pressure, or heart issues during surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 220 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2024

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * The patient is scheduled for elective robotic-assisted upper urinary tract surgery at one of the participating hospitals * The patient gives oral and written informed consent after having received oral and writen information about the study Exclusion Criteria: * The patient has a ASA-class of IV or above * The patient is a minor or declared incompetent, has severe psychiatric disease or is expected not to be able to understand the study information due to severe restrictions in vision, hearing, cognition, reading or Swedish language abilities * The patient is a female who is pregnant or breastfeeding * The patient is a pre-menopausal female who has not undergone sterilisation, hysterectomy, bilateral salpingectomy and/or bilateral oophorectomy, and is not using highly-effective contraception with low user-dependency and cannot provide a negative pregnancy test * The patient is scheduled for emergency surgery * Research staff not available * Scheduled significant simultaneous surgery on another organ * The anesthesiologist in charge has planned spinal or epidural analgesia * The patient has clear contraindications to spinal analgesia, e.g. severe coagulopathy, severe aortic stenosis, previous back surgery with rods, or spinal analgesia can be expected to be technically challenging (severe obesity, severe scoliosis) * The patient has clear contraindications to lidocaine infusion, e.g. proven allergy to local anesthetics, myasthenia gravis, renail failure (eGFR \< 30), hepatic failure caused by acute hepatitis or cirrhosis (Child-Pugh B or higher, severe cardiac arrythmias or insuffiency (NYHA IIIb or higher) * The patient has previously participated in the trial

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Benign neoplasm of ureter are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

congenital anomaly of kidney and urinary tract kidney benign neoplasm kidney cancer nephrolithiasis renal carcinoma ureter benign neoplasm ureter cancer vesicoureteral reflux

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Benign neoplasm of ureter Benign renal neoplasm Calculus of kidney and ureter Congenital ureteric anomaly Other specified disorders of kidney and ureter Renal cancer Ureter cancer Ureteric reflux

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

3 sites. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

Open the record ↗
A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Spinal shot vs IV drip: which helps you recover faster from robotic surgery?

What the study statuses mean