Neglected sense: study tests if smell checks boost health
NCT ID NCT07222891
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether helping people who have trouble smelling can improve their health and happiness. Many people don't realize their sense of smell is fading, which can affect mood, nutrition, and even safety. Researchers will give smell tests and coping advice to 1000 adults to see if it reduces depression and improves quality of life.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 1,000 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Nov 2025
An estimate. Start dates often move.
- Expected to finish
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Nov 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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7 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: \- Can read and understand English and have access to a reliable internet connection and a smart device or computer for the duration of the experimental sessions, unless they are part of community events in which smart devices are provided Exclusion Criteria: \- Known intolerance or allergy to any of the odor stimuli used
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Monell Chemical Senses Center
Philadelphia, Pennsylvania, 19104, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Brain scans may offer a new way to measure smell recovery
- A two-hour talk might boost prostate cancer screening rates
- AI app aims to boost wellbeing across eight life dimensions
- Why do we lose our sense of smell with age? scientists launch deep dive into the nose and brain.
- Shocking the nose back to life: new combo therapy for Parkinson's smell loss