Phone app aims to ease emotional burden for Alzheimer's caregivers
NCT ID NCT05949047
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a one-week smartphone training program can help unpaid caregivers of people with Alzheimer's disease better manage their emotions. Participants will be randomly assigned to learn one of two emotion-regulation techniques (distancing or reinterpretation) or to a control group. Researchers will track changes in stress, mood, and heart rate over three months to see if the training improves well-being.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- smartphone-based cognitive emotion regulation training (psychological distancing or reinterpretation)
- What this could lead to
- If it works, this could provide a simple, scalable way to reduce stress and depression in Alzheimer's caregivers, improving their quality of life.
- What could go wrong
- This is an early-stage study with no prior proof of effectiveness. The training is brief (one week), and benefits may not last or apply to all caregivers.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 270 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2023
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Healthy Adult Caregivers * Unpaid primary caregiver of patient with Alzheimer's Disease/Alzheimer's Disease and Related Dementias (AD/ADRD) * At least 18 years of age, with no maximum age, provided that all other inclusion/exclusion criteria are met * Must be able to speak, read, and write in English * Must be free of any current or past DSM diagnosis (i.e. healthy adults), with the exception of current or past mood or anxiety disorders or past substance-related disorders (i.e., current or past mood or anxiety disorders and/or past substance-related disorders would not represent an exclusion factor) * Must have a smartphone. This represents any major iOS or Android-based smartphone. The smartphone will also be used for collection of ecological momentary assessment (EMA) data via SurveySignal. * Must provide significant level of caregiving to their care recipient * Must be at least minimally-stressed Cognitively Impaired Adults * Must have diagnosed with Alzheimer's Disease/Alzheimer's Disease and Related Dementias (AD/ADRD) * Must be the care recipient of the primary caregiver who is completing the study * Must be able to understand and willing to complete a questionnaire and the consent form * Must have minimum level of dementia symptoms Exclusion Criteria: Healthy Adult Caregivers * Current or past psychiatric disorders (e.g., psychotic and personality disorders) with the exception of current or past mood or anxiety disorders or past substance-related disorders (i.e., current or past mood or anxiety disorders and/or past substance-related disorders would not represent an exclusion factor) * Currently receiving psychotherapy that specifically addresses caregiver burden/distress or employs cognitive reappraisal as a major component * Significant visual, auditory, or cognitive impairment that compromises their ability to understand and complete the task * Caregiver participants who cease meeting inclusion criteria during the study will be dismissed from the study and compensated pro-rata. * Has formerly participated in a study from our lab involving the same or essentially same design (e.g., former participants who provided pilot/preliminary data for this study) Cognitively Impaired Adults * The care recipient does not wish to participate, and/or their caregiver does not want them to participate * Significant visual, auditory, or cognitive impairment that compromises their ability to understand and complete questionnaires, even with their caregiver's help will exclude them from the study * Has formerly participated in a study from our lab involving the same or essentially same design (e.g., former participants who provided pilot/preliminary data for this study)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Rice University
RECRUITINGHouston, Texas, 77030, United States
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