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Can a smartphone help veterans walk better? new study tests home exercise for PAD

NCT ID NCT04889105

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a home-based exercise program called Smart MOVE! for Veterans with peripheral artery disease (PAD), a condition that limits walking ability. Participants will use a wearable activity monitor and receive behavioral coaching via the MOVE! program. The goal is to see if this approach can improve walking distance and be a convenient alternative to facility-based supervised exercise.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
home-based exercise therapy with mobile health monitoring and behavioral coaching
What this could lead to
If successful, this could provide a convenient, effective alternative to supervised exercise programs for improving walking ability in people with peripheral artery disease.
What could go wrong
This is a small, early feasibility study with only 75 participants. The home-based approach may not work as well as supervised therapy, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 75 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2021

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age \>40 years * Eligible Veteran status * Clinically stable intermittent claudication ( 2 months of Rutherford Class II symptoms, no evidence of chronic limb-threatening ischemia) * Established PAD diagnosis (abnormal ankle-brachial index or evidence of PAD on prior certified vascular laboratory or radiology imaging) * Access to safe location to perform walking exercises Exclusion Criteria: * Above or below knee amputation * critical limb ischemia (rest pain or tissue loss including ulceration or gangrene) * inability to walk without a walker * wheelchair confinement * non-English speaking * significant visual impairment that interferes with walking activity * hearing impairment that interferes with full study participation * unable or unwilling to return to the medical center at the expected visit frequency or unable or unwilling to use the technology required for the intervention * Individuals whose walking is limited by a condition other than PAD * Any active cardiac condition including unstable angina * unstable atrial or ventricular arrhythmias * high-grade heart block without a pacemaker * active myopericarditis * recent venous thromboembolism * or recent abnormal baseline stress test suggesting ischemia * other high-risk findings (e.g., drop of systolic blood \> 20 mmHg with exercise) * Presence of Class III NYHA heart failure or CCS III angina. * Major surgery including lower extremity revascularization or orthopedic surgery during the preceding three months or anticipated in the next nine months * Major medical illness including lung disease requiring continuous oxygen (patients wearing nighttime oxygen only may still qualify) * neurodegenerative disorders such as Parkinson's Disease that impair walking ability * cancer requiring treatment in the past 2 years (with exception for non-melanoma skin cancer or if they received treatment for early-stage cancer with an excellent overall prognosis) * Heart attack, stroke, or coronary artery bypass surgery in the preceding 3 months * Mental health illness that may interfere with the ability to consent and/or participate in the study, including mini-mental status examination score \<24 * dementia * active psychiatric disorder such as schizophrenia or bipolar disorder * history of suicidal or homicidal ideation in the preceding six months * history of suicidal attempts in the preceding 12 months * history of active substance use in the preceding six months that would interfere with study participation (as determined by their primary care or mental health provider) * Subjects endorsing SI or HI may be eligible for continued participation with monitoring if approved by their primary mental health provider * Currently walking regularly for exercise at a level comparable to the amount of exercise prescribed in the intervention * Currently enrolled in another clinical trial or structured exercise program (i.e., cardiac rehabilitation) * Deemed to be poorly suited for the study or the study intervention at the discretion of the PI or study staff

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Atlanta VA Medical and Rehab Center, Decatur, GA

    RECRUITING

    Decatur, Georgia, 30033-4004, United States

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