New adaptive radiation aims to hit cancer harder, spare healthy tissue
NCT ID NCT07324798
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing a new way to deliver radiation for prostate and bladder cancers. The approach uses an MRI-guided machine to adapt the radiation dose in real time, giving a higher boost to the tumor while sparing nearby organs. Researchers want to see if this reduces side effects and keeps cancer under control. The trial will enroll 60 adults who have not had radiation in the same area before.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- adaptive radiation therapy (MR-guided boost)
- What this could lead to
- If successful, this approach could offer a more precise radiation treatment that reduces side effects while controlling cancer effectively.
- What could go wrong
- This is an early-stage study with only 60 participants, so results may not apply broadly. The technique is complex and may not improve outcomes over standard radiation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2024
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with newly diagnosed or metastatic/recurrent pathologically confirmed urological tumors, clinically assessed as suitable for adaptive radiotherapy; * Age ≥ 18 years; * ECOG performance status score 0-2; * No prior radiotherapy history within the current radiation field; * No contraindications for MRI scanning; * No contraindications for radiotherapy. Exclusion Criteria: * Patients with contraindications to radiotherapy; * Patients unable to tolerate MRI or with contraindications to MRI scanning.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Cancer Hospital, National Cancer Center, CAMS & PUMC
RECRUITINGBeijing, Beijing Municipality, 100021, China
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Other studies related to the condition(s) this trial covers.
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