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Tiny brain strokes linked to heart hole in young adults

NCT ID NCT04043559

Knowledge-focused Sponsor: Centre Hospitalier Universitaire de Nīmes Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 50 young adults (under 60) who had a stroke with no clear cause. Researchers wanted to see if small strokes in the cerebellum (back part of the brain) were linked to a common heart condition called PFO (a small hole between the heart's upper chambers). They compared patients with and without PFO to find patterns in stroke location and size.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

50 people

The number who actually took part.

Started

Jul 2019

Finished

Dec 2019

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Consecutive young (\<60 years) cryptogenic stroke patients with PFO recruited between January 2016 and May 2019 in our center, and compared these patients with sex- and age-matched controls with cryptogenic stroke without PFO.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patients : young (\<60 years) adult patients, * Patient recruited and registered in our stroke database between January 2016 and May 2016 of our center (Nîmes University Hospital, France), * Patients presenting with an acute symptomatic infarction (confirmed by diffusion-weighted MRI) of unknown origin * Controls : age-matched controls with cryptogenic stroke without PFO

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Conditions

The condition(s) this trial relates to.

brain infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brain infarction

Contacts and locations

Locations

  • CHU Nîmes

    Nîmes, 30029, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.