Zapping sleep to lift depression brain fog?
NCT ID NCT07143838
First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times
Summary
This small study tests if a non-invasive device that stimulates the brain during sleep can increase deep sleep in adults with depression. Researchers want to see if better deep sleep helps with memory, thinking, and mood. Participants wear a headband and activity tracker at home and complete thinking tests and questionnaires.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 12 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Ability to complete overnight sleep study including placement of EEG leads * Ability to read and understand English. * Moderate depression * Self-reported cognitive complaints Exclusion Criteria: * Previous adverse reaction to transcranial electrical stimulation * Presence of implanted devices (e.g. intracranial device, cochlear implant) * Presence of metal in head (e.g. surgical clip) * Sensitivity or allergy to silver * Presence of significant neurologic disease (e.g. Parkinson's disease, epilepsy/seizure disorder, severe migraine disorder) * History of significant head trauma * History of stroke or other ischemic event * Diagnosed with schizophrenia, bipolar disorder, substance use disorder, or presence of current suicidal ideation * Currently taking medications that could alter EEG or cognitive function * Presence of severe insomnia * Presence of severe, untreated sleep apnea * Currently pregnant * Planned travel outside time zone during the study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Wake Forest University Health Sciences
RECRUITINGWinston-Salem, North Carolina, 27104, United States
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