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Sleep apnea linked to hidden heart damage, study finds

NCT ID NCT01089257

Knowledge-focused Sponsor: University Hospital, Grenoble Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aimed to find early signs of heart and blood vessel damage in people with obstructive sleep apnea, before serious symptoms appear. Researchers planned to follow 133 patients and check if CPAP treatment could reverse these early changes. The study was terminated early, so results are limited.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

133 people

The number who actually took part.

Started

Nov 2007

Finished

Jun 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with obstructive sleep apnea syndrome (Apnea/Hypopnea index \> 15)

Ages

18 to 78 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female from 18 to 78 years old * Patients with obstructive sleep apnea syndrome (Apnea/Hypopnea index \> 15) * ambulatory patients * patients who have signed the inform consent form * patients with health insurance Exclusion Criteria: * Body Mass Index upper or equal to 30 * cardiovascular pathology except blood pressure hypertension * known or treated diabetes * pathologies with consequence on blood pressure regulation * drugs intakes with consequence on blood pressure regulation * patient with chronic obstructive pulmonary disease * atrial fibrillation or more than 10/minute extrasystoles * bedridden patients or patients with decreased mobility * patients working at night or with shift work * patients with carotid stenting or surgery history * patients unable to sign the inform consent form * patients already treated by cPAP or dental appliance for OSAS in the last 6 months * pregnant or suckling female * patients under supervision or trusteeship * patients taking part in another clinical trial

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Conditions

The condition(s) this trial relates to.

obstructive sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obstructive sleep apnea syndrome Subclinical cardiovascular impairments

Contacts and locations

Locations

  • France : Laboratoire EFCR - Functional cardiorespiratory explorations laboratory

    Grenoble, 38000, France

  • France : Laboratoire EFCR - Functional cardiorespiratory explorations laboratory

    Saint-Etienne, 42000, France

  • France : Laboratoire d'explorations fonctionnelles du système nerveux - Functional explorations laboratory of nervous system

    Clermont-Ferrand, 63000, France

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Other studies related to the condition(s) this trial covers.