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New drug duo shows promise for tough breast cancers

NCT ID NCT05445908

First seen Nov 17, 2025 · Last updated Jun 12, 2026 · Updated 27 times

Summary

This study tests a new drug (SKB264) alone or with another drug (KL-A167) in people with advanced HER2-negative breast cancer that hasn't been treated yet. The goal is to see if the combination is safe and shrinks tumors. About 175 adults with triple-negative or HR+/HER2- breast cancer will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hunan Cancer Hospital

    Changsha, Hunan, 410031, China

  • Jiangsu Province Hospital

    Nanjing, Jiangsu, 210029, China

Conditions

The condition(s) this trial relates to.

triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.