New study aims to uncover mysteries of rare SITRAME syndrome
NCT ID NCT07168746
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study will collect information from 100 people in France with SITRAME syndrome, a rare autoinflammatory disease. Researchers want to learn about the disease's symptoms, treatments, and outcomes. No new treatments are being tested; the goal is simply to better understand the condition.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could provide the first clear picture of how SITRAME syndrome affects people in France, helping doctors recognize and manage it better.
- What could go wrong
- This is an observational study, not a treatment trial. It will not test any new therapy, and results may take years to gather and analyze.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2025
An estimate. Start dates often move.
- Expected to finish
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Sep 2055
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients will be recruited in France via the national reference center for autoinflammatory diseases at Tenon Hospital (Internal Medicine, Dermatology and Allergology Department at Tenon Hospital).
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: • SITRAME syndrome meeting the diagnostic criteria for the disease All the following criteria must be met: 1. Systemic inflammation: at least 1 documented episode of CRP \>5mg/mL during a skin flare 2. Maculopapular rash on the trunk: fixed, non-itchy maculopapular rash on the trunk appearing within hours with clear borders 3. Recurrence in the same areas: at least 3 different episodes 4. Acute: duration less than 8 days And at least 1 of the following criteria: 1. Fever during flare-ups 2. Flare-ups triggered by infections, vaccinations, or intense physical exercise 3. Fatigue during and/or after flare-ups 4. Associated papular rash And all the following exclusion criteria must be met: * No evidence of a monogenic autoinflammatory disease, evolving neoplasm, or evolving autoimmune disease. * Adult patients at the time of inclusion * Patients not opposed to participating in the research Exclusion Criteria: \- Persons with special protection cannot be included in the study: * Adults under guardianship or curatorship * Hospitalized persons without consent and not legally protected * Persons deprived of liberty
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.