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Can a diabetes drug help fight liver cancer? early safety trial completed

NCT ID NCT02650427

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 39 times

Summary

This early study tested whether a 3-week course of sitagliptin, a diabetes drug, is safe for people with liver cancer (HCC) who are having part of their liver removed. Only 14 patients took part. The goal was to see if the drug could help the immune system attack the tumor by protecting a key immune signal. The study focused on safety and immune cell activity, not on curing the cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Pitié-Salpêtrière Hospital

    Paris, 75013, France

Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.