Can a transplant drug slow rare muscle disease?
NCT ID NCT04789070
First seen Jan 19, 2026 · Last updated May 18, 2026 · Updated 16 times
Summary
This phase 3 trial tests whether sirolimus, a drug used in organ transplants, can slow or stop muscle decline in people with inclusion body myositis (IBM), a rare muscle disease. About 140 adults aged 45 and older will take sirolimus or a placebo for 84 weeks. The study measures changes in muscle function, walking ability, and daily tasks to see if the drug helps maintain independence.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Austin Health
Melbourne, Victoria, Australia
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Concord Repatriation Hospital
Sydney, New South Wales, Australia
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Johns Hopkins University
Baltimore, Maryland, 21218, United States
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Leiden University Medical Center
Leiden, Netherlands
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Perron Institute
Perth, Washington, Australia
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Royal Adelaide Hospital
Adelaide, South Australia, Australia
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Royal Brisbane and Women's Hospital
Brisbane, Queensland, Australia
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Royal Northshore Hospital
Sydney, New South Wales, Australia
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St Vincent's Hospital
Melbourne, Victoria, Australia
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University of Kansas Medical Center
Kansas City, Kansas, 66160, United States
Conditions
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