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Can tiny silicon particles make 3D-Printed dentures cleaner and more comfortable?

NCT ID NCT07817420

Symptom relief Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 14, 2026 · Last updated Sep 15, 2026 · Updated 1 time

Summary

Researchers at Mansoura University are comparing two types of 3D-printed acrylic denture bases for implant-retained lower overdentures. One base is standard, and the other has 0.5% silicon dioxide nanoparticles mixed in. The study enrolls 20 completely edentulous adults who receive two lower implants to hold their overdentures. The team measures surface roughness of the denture base and checks gum health, plaque, and bacterial levels around the implants to see whether the nanoparticle version performs better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
silicon dioxide nanoparticles added to a 3D-printed acrylic denture base material
What this could lead to
If the nanoparticle-modified material performs better, it could offer a smoother, more hygienic denture base option for people who wear implant-retained overdentures.
What could go wrong
This is a small, single-center study of 20 participants, so the results may not hold up in larger or longer trials. Nanoparticle-modified dental materials also need long-term safety checks before routine use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Feb 2023

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Dentally Edentulous Status: Completely edentulous patients in both arches requiring a maxillary complete denture and a mandibular implant-retained overdenture. * Bone Volume: Patients with adequate mandibular bone height and width to accommodate bilateral implant placement in the canine region. * General Health: Good general health status permitting standard dental implant surgical procedures. * Oral Hygiene: Acceptable oral hygiene status and motivation to maintain oral health. * Compliance: Patient willingness and capability to comply with all scheduled follow-up visits and clinical evaluations. Exclusion Criteria: * Systemic Health Conditions: Patients with compromised systemic conditions or uncontrolled systemic diseases that adversely affect bone healing, soft tissue response, or osseointegration (e.g., uncontrolled diabetes mellitus). * Oncological Therapy: History of previous head and neck radiotherapy or active/past chemotherapy. * Tobacco Use: Heavy smoking * Parafunctional Habits: Presence of severe bruxism or other parafunctional oral habits. * Patient Compliance: Poor patient compliance or inability/unwillingness to commit to the required follow-up schedule and maintenance protocols.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Edentulism; implant-retained mandibular overdentures

Contacts and locations

Locations

  • Mansoura university faculty of dentistry

    Al Mansurah, 35511, Egypt