Can tiny silicon particles make 3D-Printed dentures cleaner and more comfortable?
NCT ID NCT07817420
First seen Sep 14, 2026 · Last updated Sep 15, 2026 · Updated 1 time
Summary
Researchers at Mansoura University are comparing two types of 3D-printed acrylic denture bases for implant-retained lower overdentures. One base is standard, and the other has 0.5% silicon dioxide nanoparticles mixed in. The study enrolls 20 completely edentulous adults who receive two lower implants to hold their overdentures. The team measures surface roughness of the denture base and checks gum health, plaque, and bacterial levels around the implants to see whether the nanoparticle version performs better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- silicon dioxide nanoparticles added to a 3D-printed acrylic denture base material
- What this could lead to
- If the nanoparticle-modified material performs better, it could offer a smoother, more hygienic denture base option for people who wear implant-retained overdentures.
- What could go wrong
- This is a small, single-center study of 20 participants, so the results may not hold up in larger or longer trials. Nanoparticle-modified dental materials also need long-term safety checks before routine use.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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20 people
The number who actually took part.
- Started
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Feb 2023
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Dentally Edentulous Status: Completely edentulous patients in both arches requiring a maxillary complete denture and a mandibular implant-retained overdenture. * Bone Volume: Patients with adequate mandibular bone height and width to accommodate bilateral implant placement in the canine region. * General Health: Good general health status permitting standard dental implant surgical procedures. * Oral Hygiene: Acceptable oral hygiene status and motivation to maintain oral health. * Compliance: Patient willingness and capability to comply with all scheduled follow-up visits and clinical evaluations. Exclusion Criteria: * Systemic Health Conditions: Patients with compromised systemic conditions or uncontrolled systemic diseases that adversely affect bone healing, soft tissue response, or osseointegration (e.g., uncontrolled diabetes mellitus). * Oncological Therapy: History of previous head and neck radiotherapy or active/past chemotherapy. * Tobacco Use: Heavy smoking * Parafunctional Habits: Presence of severe bruxism or other parafunctional oral habits. * Patient Compliance: Poor patient compliance or inability/unwillingness to commit to the required follow-up schedule and maintenance protocols.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Mansoura university faculty of dentistry
Al Mansurah, 35511, Egypt