Natural blood product may improve dental implant success in sinus lifts
NCT ID NCT07367217
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new method using albumin platelet-rich fibrin (A-PRF) for sinus lift surgery before placing dental implants. Thirty-two patients with limited jawbone height received either A-PRF or a standard allograft. The goal was to see which approach gives better implant stability and bone growth over two years.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- albumin platelet-rich fibrin (A-PRF)
- What this could lead to
- If successful, this could offer a simpler, more natural option for sinus lifts before dental implants, potentially reducing the need for synthetic materials.
- What could go wrong
- This is a small, completed study with only 32 participants, so results may not apply to everyone. The procedure still carries standard surgical risks like infection or implant failure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
32 people
The number who actually took part.
- Started
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Sep 2023
- Finished
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Nov 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patent ostium of maxillary sinus. * Patient with missing one or more posterior maxillary teeth. * Residual bone height of 3-6 mm, measured from the crest of alveolar ridge to the floor of the maxillary sinus at the planned implant site. * A ridge width at the site of implantation of \<5mm. * Platelets of normal range. * Good oral hygiene. * Patients in the age frame between 20 years and 60 years old. * No gender preface in selection of the patients. * A minimum crown height space of 8 mm. Exclusion Criteria: * Active sinusitis, cyst, tumors or root tips at the planned surgical site. * Patients with systemic diseases that contra-indicate the surgical procedure such as uncontrolled diabetes mellitus, bleeding disorders, serious osseous disorders, and mental disorders. * Heavy smoking and alcoholism. * Parafunctional habits such as bruxism and clenching. * Signs of acute infection or pus discharge. * Disturbed occlusion.
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mansoura University
Al Mansurah, 002, Egypt
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