Pig or cow bone? new study tests best graft for dental implants
NCT ID NCT07386184
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests two types of bone graft materials—one from pigs and one from cows—used in sinus lift surgery to prepare for dental implants. Twenty-four healthy volunteers needing implants in the upper jaw will receive one of the grafts. After six months, a small bone sample will be taken to see how well the graft turned into new bone. The goal is to find out which material works better for bone regeneration.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- collagenic porcine graft and collagen-enriched bovine-derived graft
- What this could lead to
- If it works, this could point toward a better bone graft material for dental implants, improving success rates and reducing complications.
- What could go wrong
- This is a small, early-stage study with only 24 participants, so results may not apply to everyone. The grafts might not integrate well or could cause inflammation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 24 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient requiring vertical elevation of the maxillary sinus floor. * Residual alveolar bone height of edentulous maxilla below the floor of the maxillary sinus \<5 mm. * Males and females between 30-80 years old * Patients with healthy periodontal conditions (treated periodontitis, PI\<25%, BoP\<25%). * Patients willing to sign an informed consent and participate in a clinical study. * Generally fit and healthy and able to undergo oral surgical procedures under local anesthesia. * Teeth at the surgical site requiring extraction were removed at least 12 weeks prior to sinus floor elevation. Exclusion Criteria: * Patients who smoke more than 5 cigarettes/day * Pregnancy (confirmed by verbal inquiry) * Chronic systemic pathologies (e.g. diabetes) and neoplasms of the oro-facial district. * Patients undergoing treatment with antiresorptive agents. * Patients receiving systemic corticosteroid therapy. * Any site with a history of implant failure. * Dental sites with acute infections. * Chronic inflammatory diseases of the oral cavity. * Autoimmune diseases. * Documented hypersensitivity to any of the medications intended for use during the treatment protocol. * Substance abusers. * Patients with known collagen hypersensitivity. * Patients with hypersensitivity to porcine-derived materials. * History of malignant tumors of the maxillary sinus. * History of head/neck radiation therapy.
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
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The official record
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A doctor treating you
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