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One set or many? study tests best way to build muscle in sedentary men

NCT ID NCT07337304

First seen Jan 19, 2026 · Last updated Jun 23, 2026 · Updated 24 times

Summary

This study compared doing one set versus multiple sets of resistance exercises in 34 sedentary men aged 18-40. Participants were randomly assigned to a single-set group, a multiple-set group, or a no-exercise control group. Researchers measured changes in muscle strength, size, and power after a structured training program. The goal was to find the optimal training volume for beginners.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Inonu University, Faculty of Sport Sciences

    Malatya, 44280, Turkey (Türkiye)

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Resistance training (structured exercise program using free weights and machines)

What this could lead to

If successful, this study could help determine the most effective number of exercise sets for building strength and muscle in people new to training.

What could go wrong

This is a small, completed study with only 34 participants. Results may not apply to women, older adults, or trained individuals. No long-term follow-up was done.

Conditions

The condition(s) this trial relates to.

Sedentary Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.