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One set or many? study tests best way to build muscle in sedentary men

NCT ID NCT07337304

Knowledge-focused Sponsor: Inonu University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared doing one set versus multiple sets of resistance exercises in 34 sedentary men aged 18-40. Participants were randomly assigned to a single-set group, a multiple-set group, or a no-exercise control group. Researchers measured changes in muscle strength, size, and power after a structured training program. The goal was to find the optimal training volume for beginners.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Resistance training (structured exercise program using free weights and machines)
What this could lead to
If successful, this study could help determine the most effective number of exercise sets for building strength and muscle in people new to training.
What could go wrong
This is a small, completed study with only 34 participants. Results may not apply to women, older adults, or trained individuals. No long-term follow-up was done.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

34 people

The number who actually took part.

Started

Aug 2022

Finished

Dec 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male participants aged between 18 and 40 years * Sedentary lifestyle (no structured resistance training in the previous 6 months) * Apparently healthy, with no known cardiovascular, metabolic, or musculoskeletal disorders * Ability to participate in resistance training exercise * Willingness to provide written informed consent Exclusion Criteria: * Participation in regular resistance or structured exercise training within the past 6 months * History of musculoskeletal injury or surgery that could limit exercise performance * Presence of cardiovascular, neurological, or metabolic disease * Use of medications or supplements known to affect muscle function or performance * Any condition deemed unsafe for participation by the investigators

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Conditions

The condition(s) this trial relates to.

Sedentary Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neuromuscular adaptations Resistance training adaptation Sedentary lifestyle

Contacts and locations

Locations

  • Inonu University, Faculty of Sport Sciences

    Malatya, 44280, Turkey (Türkiye)

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