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Common heart drug may hold key to staving off liver failure

NCT ID NCT03654053

Summary

This study is testing whether simvastatin, a medication typically used to lower cholesterol, can help prevent liver failure in U.S. veterans who have early-stage cirrhosis (scarred liver) but no symptoms yet. About 142 participants with a high risk of their liver disease worsening will take either simvastatin or a placebo pill daily for up to two years. Researchers will track whether the drug delays serious liver complications, liver cancer, or death, and will monitor for side effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brooklyn Campus of the VA NY Harbor Healthcare System, Brooklyn, NY

    Brooklyn, New York, 11209, United States

  • Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA

    Philadelphia, Pennsylvania, 19104-4551, United States

  • Hunter Holmes McGuire VA Medical Center, Richmond, VA

    Richmond, Virginia, 23249, United States

  • James J. Peters VA Medical Center, Bronx, NY

    The Bronx, New York, 10468, United States

  • Michael E. DeBakey VA Medical Center, Houston, TX

    Houston, Texas, 77030, United States

  • Philadelphia MultiService Center, Philadelphia, PA

    Philadelphia, Pennsylvania, 19106, United States

  • Robley Rex VA Medical Center, Louisville, KY

    Louisville, Kentucky, 40206, United States

  • San Francisco VA Medical Center, San Francisco, CA

    San Francisco, California, 94121, United States

  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA

    Boston, Massachusetts, 02130, United States

  • VA Connecticut Healthcare System West Haven Campus, West Haven, CT

    West Haven, Connecticut, 06516, United States

  • VA Puget Sound Health Care System Seattle Division, Seattle, WA

    Seattle, Washington, 98108, United States

Conditions

Explore the condition pages connected to this study.