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Can nanotechnology silver beat standard gauze for diabetic foot ulcers?

NCT ID NCT07758855

Disease control Sponsor: Ankara City Hospital Bilkent Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This trial compares a new silver-coated dressing made with nanotechnology to a standard saline-moistened gauze for treating infected diabetic foot ulcers. Adults with moderate (PEDIS grade 2 or 3) ulcers will receive either the silver dressing or conventional gauze, changed every 3 days for 21 days, alongside routine diabetic foot care. Researchers will measure changes in wound size, infection levels, and tissue health to see if the silver dressing improves healing and reduces infection better than standard care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A silver-coated wound dressing made with nanotechnology, applied directly to the ulcer and changed every 3 days for 21 days.
What this could lead to
If effective, this dressing could offer a better way to treat infected diabetic foot ulcers, potentially reducing the need for amputation and improving healing outcomes.
What could go wrong
This is a relatively small, early-stage study, and results may not apply to all patients. The dressing might not outperform standard care, and there is a risk of allergic reactions or skin irritation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

107 people

The number who actually took part.

Started

May 2024

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged over 18 years * Able and willing to give written informed consent * PEDIS grade 2 or PEDIS grade 3 diabetic foot ulcer on either foot Exclusion Criteria: * Aged under 18 years * Known allergy to silver or to polyester * Pregnancy * Non-infected PEDIS grade 1 ulcer * PEDIS grade 4 ulcer, on the grounds of metabolic instability

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Conditions

The condition(s) this trial relates to.

Diabetic Foot

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diabetic ulcers on both feet

Contacts and locations

Locations

  • Ankara Bilkent City Hospital, Department of General Surgery

    Ankara, Cankaya, 06800, Turkey (Türkiye)