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Sibling power: could brothers and sisters be the key to autism therapy?

NCT ID NCT05098392

Symptom relief Sponsor: Arizona State University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study explored whether training typically developing siblings to teach reading and social skills can help children with autism. The approach used a simple teaching method called model-lead-test, where the sibling shows, practices, and gives feedback. Only 8 families took part, and the study was stopped early, so the findings are not conclusive.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
sibling-mediated behavioral intervention
What this could lead to
If successful, this approach could offer a low-cost, natural way to improve reading and social skills in children with autism using sibling support.
What could go wrong
The study was terminated early and enrolled only 8 participants, so results are very limited. It is unclear if the intervention works broadly or has lasting effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

8 people

The number who actually took part.

Started

Nov 2021

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

5 to 11 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Both siblings can demonstrate compliance during instruction. * Children with ASD can imitate physical actions and repeat vocalizations, answering common questions, label common objects and actions with adjectives. * Typically developing children can sound out and blend letters during reading. Exclusion Criteria: * Children with aggression towards their siblings and noncompliance during instruction * Children with ASD who can sound out and blend letters.

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Conditions

The condition(s) this trial relates to.

autism spectrum disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Autism spectrum disorder

Contacts and locations

Locations

  • Best Love Child Development Center

    Kunming, Yunnan, China

  • Children's Autism Center

    Round Rock, Texas, 78664, United States

  • Clover Children Rehabilitation Kindergarten

    Shanghai, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.