Brain stent blood thinner study pulled before it began
NCT ID NCT06857045
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study planned to compare taking blood thinners for 3 months versus 6 months after placing a special drug-coated stent in a narrowed brain artery. The goal was to see if the shorter treatment was just as good at preventing strokes and bleeding. However, the trial was withdrawn before any patients were enrolled, so no conclusions can be drawn.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dual antiplatelet therapy (blood thinners)
- What this could lead to
- If successful, this could show that a shorter course of blood thinners after brain stenting is as safe and effective as a longer course, reducing bleeding risk.
- What could go wrong
- The trial was withdrawn before any participants were enrolled, so no data was collected. It is unknown whether the shorter treatment would have been safe or effective.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Started
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Jul 2024
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 85 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria 1. Males or females between 35 and 80 years of age. 2. Symptomatic intracranial arteriosclerosis stenosis with reference diameter 2.25-4.00mm;. 3. Intracranial artery stenosis (≥70%) conformed by DSA. 4. Subjects who voluntarily participate in the study and sign informed consent form. Exclusion Criteria: 1. Subjects who have surgery within previous 30 days or plan to perform major surgery in the next 90 days (surgery grade 3 and above). 2. Subjects of acute hemorrhagic stroke within 3 months. 3. Disabling stroke with a baseline mRS score ≥3. 4. Lesion artery with severe calcification and close neighbour stenosis. 5. Non-atherosclerotic diseases (e.g. arterial dissection, Moya Moya disease, vascular inflammatory lesions caused by infection, autoimmune diseases, post-irradiation, postpartum status; developmental or genetic abnormalities such as fibromuscular dysplasia, sickle cell anemia, suspected vasospasm). 6. The ischaemic event that is highly suspected to be due to vascular embolism from an extracranial arterial segment such as ipsilateral neck/chest arterial occlusion) or cardio embolism such as atrial fibrillation, mitral stenosis, left ventricular thrombus, patent foramen ovale, myocardial infarction within 6 weeks, etc. 7. More than 50% stenosis of the supplying artery of the lesion artery: 1) MCA severe stenosis (lesion artery) with more than 50% stenosis of ipsilateral ICA (supplying artery). 2) Basilar artery severe stenosis (lesion artery) with more than 50% stenosis of dominant VA (supplying artery) stenosis. 8. Accompanied by intracranial tumours or intracranial arteriovenous malformations. 9. The patient who is allergy response to heparin, aspirin, clopidogrel, rapamycin, contrast agents, anaesthetics, or drug eluted stent components. 10. Women who are pregnant or lactating. 11. Due to cognitive or emotional disorders or mental illness, the patient who cannot finish the follow-up. 12. Investigators consider the patient who is not suitable for enrolling in the present trial.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The Fourth Affiliated Hospital of China Medical University
Ha’erbin, China
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Other studies related to the condition(s) this trial covers.
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