Spinal zaps plus pills may ease stroke pain
NCT ID NCT07593313
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding short-term spinal cord stimulation to standard pain medication can better reduce central post-stroke pain. About 80 adults with this type of pain will be randomly assigned to receive either the stimulation plus medication or medication alone. The main goal is to see if pain scores drop more right after treatment and up to 6 months later.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2024
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosis of central post-stroke pain (CPSP) according to the International Association for the Study of Pain (IASP) criteria * Clear history of stroke confirmed by cranial CT or MRI * Pain occurring after stroke and distributed in body parts corresponding to central nervous system injury * Pain with neuropathic characteristics (e.g., burning sensation, electric shock sensation, needle prick sensation) * Pain not explained by other causes * Age ≥ 18 years * Pain duration ≥ 3 months * Baseline pain Numerical Rating Scale (NRS) score ≥ 4 points * Complete clinical data with follow-up time ≥ 6 months Exclusion Criteria: * History of chronic pain before stroke * Severe cognitive impairment that prevents cooperation with pain assessment (Mini-Mental State Examination, MMSE \< 15 points) * Contraindications to spinal cord stimulation (SCS), such as coagulation disorders, active infections, or mental diseases that prevent cooperation * Malignant tumors or other severe organic diseases with expected survival \< 1 year
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Nanchong Central Hospital
RECRUITINGNanchong, Sichuan, 637000, China
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