Shockwave therapy could ease lipedema symptoms in new trial
NCT ID NCT07240415
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding shockwave therapy to standard care (like compression and massage) can reduce pain and swelling in women with lipedema. Fifty women aged 18-65 with early-stage lipedema will be randomly assigned to receive either standard care alone or standard care plus shockwave therapy twice a week for four weeks. Researchers will measure changes in limb size, pain, and quality of life over eight weeks.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- radial extracorporeal shockwave therapy (ESWT)
- What this could lead to
- If it works, this could offer a new, non-invasive option to ease pain and improve quality of life for women with lipedema.
- What could go wrong
- This is a small, early-stage trial with only 50 people. The shockwave therapy may not provide significant extra benefit over standard care, and results may not apply to all lipedema patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Female patients aged 18-65 years Diagnosis of primary lipedema (Stage I-II according to Wold criteria) Stable body weight for the past 3 months Ability to comply with compression garment use Willingness to participate and ability to provide informed consent Exclusion Criteria: Secondary lipedema or severe venous disease (CEAP C4 or higher) Liposuction or similar procedures within the past 6 months Pregnancy or breastfeeding Active infection, inflammation, or thrombosis Use of high-dose anticoagulants Contraindications to extracorporeal shockwave therapy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a 12-Item quiz capture daily life with lipedema?
- Can a Self-Drainage routine match Therapist-Led care for lipedema?
- Lipedema and muscle loss: is there a hidden link?
- A blood test clue to unmask lipedema?
- Could lipedema weaken bones? a new study investigates