Can the shingles vaccine be safe for lupus patients? new trial aims to find out
NCT ID NCT05559671
First seen Jan 11, 2026 · Last updated Jun 22, 2026 · Updated 19 times
Summary
This study is testing whether the Shingrix vaccine, which protects against shingles, is safe for people with systemic lupus erythematosus (SLE). Researchers want to see if the vaccine causes lupus flare-ups. The trial will involve 224 adults with lupus, who will receive either the vaccine or a placebo. The goal is to ensure that people with lupus can safely get this important vaccine.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SYSTEMIC LUPUS ERYTHEMATOSUS are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
Contact
-
Oklahoma Medical Research Foundation
RECRUITINGOklahoma City, Oklahoma, 73104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Shingrix (herpes zoster subunit vaccine)
What this could lead to
If successful, this could show that the Shingrix vaccine is safe for people with lupus, allowing them to get protected against shingles without worsening their lupus.
What could go wrong
This is a Phase 4 study, so the vaccine is already approved for others. The main concern is whether it might trigger lupus flares in some patients. Results may not apply to all lupus patients, especially those on strong immunosuppressants.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.