Nearly 10,000 heart attack patients to test ancient pill for better recovery
NCT ID NCT07153744
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This large study will test whether adding Shexiang Baoxin Pill (Muskardia) to standard treatment helps people who have had a heart attack. About 9,588 participants will receive either standard care alone or standard care plus the pill for 12 months. The goal is to see if the pill lowers the chance of further heart problems, stroke, or death.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Shexiang Baoxin Pill (Muskardia)
- What this could lead to
- If it works, this could provide a new add-on treatment to reduce the risk of further heart problems and improve recovery after a heart attack.
- What could go wrong
- This is a phase 4 real-world study, so it builds on existing knowledge rather than testing a brand-new approach. The pill may not significantly lower complication rates beyond standard care, and individual results may vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
-
About 9,588 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Sep 2025
An estimate. Start dates often move.
- Expected to finish
-
Dec 2029
An estimate. End dates often move.
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 18 years or older, regardless of gender * In accordance with the 2023 ESC Guidelines for the Management of Acute Coronary Syndromes , meeting the diagnostic criteria for acute myocardial infarction, including typical chest pain lasting for ≥20 minutes, electrocardiographic manifestations of ST-segment elevation (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI), and serum high-sensitivity troponin (hs-cTn) levels exceeding the 99th percentile of the upper reference limit at least once with dynamic changes * Presenting for treatment within \<24 hours of symptom onset and scheduled to undergo PCI * The patient or their guardian has signed the informed consent form Exclusion Criteria: * Having contraindications to PCI treatment * Being allergic to Shexiang Baoxin Pills, unable to tolerate them, or having other conditions that prevent completion of the trial drug administration * Being pregnant, planning to become pregnant, or breastfeeding women * Having participated in other clinical studies within 3 months * Being deemed unsuitable for inclusion in this study by the researcher
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Acute myocardial infarction (AMI) are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Zhongshan Hospital, Fudan University
Shanghai, 200032, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A temporary wire that keeps hearts beating on cue
- AI may spot deadly heart rhythms before they strike
- Could a Drug-Coated balloon beat stents for a common heart attack cause?
- Antioxidant infusion may shield the heart from reperfusion injury
- Could cold climates shape heart healing after stents?
- Can a temporary heart pump save more lives in cardiogenic shock?