Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Brain scans reveal overlap in social thinking in autism and schizophrenia

NCT ID NCT07618767

Knowledge-focused Sponsor: National Taiwan University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study uses brain scans and behavioral data from 267 adults (80 with autism, 79 with schizophrenia, and 108 healthy controls) to explore shared brain activity patterns related to social thinking. No new treatments are given; researchers analyze existing data to understand how social difficulties may arise from similar brain mechanisms in both conditions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help researchers better understand the brain mechanisms behind social challenges in autism and schizophrenia, potentially guiding future treatments.
What could go wrong
This is an observational study using existing data, not a clinical trial testing a new treatment. It may not lead to direct patient benefits or new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

267 people

The number who actually took part.

Started

Sep 2025

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This retrospective cohort study will use pre-existing clinical, behavioral, and neuroimaging data from adult participants who were previously enrolled in cohort studies conducted at National Taiwan University Hospital. The study population includes adults with autism spectrum disorder, adults with schizophrenia, and healthy control participants. Available data include structural MRI, resting-state functional MRI, and symptom or behavioral assessments relevant to social cognition and psychiatric symptoms, including the Social Responsiveness Scale and the Positive and Negative Syndrome Scale when applicable. No new participants will be prospectively recruited, and no intervention will be administered.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Previously enrolled in one of the source cohort studies approved by the institutional review board of National Taiwan University Hospital. * Adult participants belonging to one of the following groups: 1. Autism spectrum disorder group: participants with a clinical diagnosis of autism spectrum disorder according to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria. 2. Schizophrenia group: participants with a clinical diagnosis of schizophrenia according to DSM-5 criteria. 3. Healthy control group: participants without a history of autism spectrum disorder, schizophrenia, or other major psychiatric or neurodevelopmental disorders according to available source cohort records. * Availability of resting-state functional MRI data acquired under the study MRI protocol. * For participants in the autism spectrum disorder group, availability of autistic trait or social functioning measures, such as the Social Responsiveness Scale, when used in symptom-association analyses. * For participants in the schizophrenia group, availability of psychiatric symptom measures, such as the Positive and Negative Syndrome Scale, when used in symptom-association analyses. Exclusion Criteria: * Missing or incomplete MRI data. * Poor-quality MRI data due to severe artifacts, failed preprocessing, failed registration, or incomplete brain coverage. * Excessive head motion during resting-state fMRI that prevents reliable analysis. * Missing essential demographic or diagnostic information. * Missing required clinical or behavioral measures for specific association analyses. * Healthy controls with documented major psychiatric or neurodevelopmental disorders, if identified in source cohort records.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Autism spectrum disorder are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

autism spectrum disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Autism spectrum disorder Schizophrenia

Contacts and locations

Locations

  • National Taiwan University Hospital

    Taipei, 100, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.