Could your menstrual cycle affect MS symptoms? new study investigates
NCT ID NCT07081594
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how natural hormone changes during the menstrual cycle impact brain-to-muscle communication, learning new motor skills, and fatigue in women with multiple sclerosis. Researchers will measure these factors at different cycle phases in 14 participants. The goal is to understand if certain phases are better for rehabilitation, potentially leading to more personalized therapy timing.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help tailor rehabilitation timing to menstrual cycles for better outcomes in females with MS.
- What could go wrong
- This is a very small observational study (14 participants) and only looks at short-term effects. Results may not apply to all people with MS.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 14 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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Mar 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Persons with menstrual cycles and any form of multiple sclerosis
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥18 years * Diagnosis of relapsing-remitting, primary progressive or secondary progressive MS with no minimum years since diagnosis * Stable disease modifying therapies for at least 6 months * Eumenorrheic females Exclusion Criteria: * Another diagnosis (e.g., peripheral neuropathies or orthopedic) * Pregnancy as confirmed by urine test * Irregular menstrual cycles * Diagnosis of premenstrual dysphoric disorder or polycystic ovary syndrome * Taking antipsychotic medications / does not pass the TMS safety checklist
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Shirley Ryan AbilityLab
Chicago, Illinois, 60611, United States
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Other studies related to the condition(s) this trial covers.
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