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Nerve zapping for depression: does sex matter?

NCT ID NCT04448327

First seen Jan 08, 2026 · Last updated May 22, 2026 · Updated 32 times

Summary

This study looked at how a gentle nerve stimulation device (tVNS) affects the brain's stress response in people with major depression. Researchers tested 62 adults, comparing active stimulation to a sham (fake) version while scanning their brains. The goal was to see if the effects differ between men and women, helping to understand how depression works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Massachusetts General Hospital

    Charlestown, Massachusetts, 02129, United States

Conditions

Explore the condition pages connected to this study.