Which anesthetic keeps pain tracking more accurate? new study aims to find out
NCT ID NCT07511634
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will compare two common anesthetics, sevoflurane and desflurane, to see how they affect a pain monitoring tool called the Analgesia Nociception Index (ANI) during surgery. About 80 adults undergoing general anesthesia will be randomly assigned to receive one of the two drugs. The goal is to understand which anesthetic allows for better pain assessment, which could help doctors tailor anesthesia more precisely.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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19 to 79 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 19 to 79 years * Patients undergoing general anesthesia * American Society of Anesthesiologists (ASA) physical status I or II Exclusion Criteria: * History of taking medications that may affect the central nervous system or autonomic nervous system (e.g., anticholinergics, beta-blockers, antidepressants, anxiolytics, hypnotics, or analgesics) * Known hypersensitivity to sevoflurane, desflurane, or other halogenated anesthetics, or a personal or family history of malignant hyperthermia * Neurologic or psychiatric disorders (e.g., depression, dementia, or cerebral infarction) * Arrhythmia * Diabetes mellitus * Drug abuse or alcohol abuse * Vulnerable subjects * Patients aged 80 years or older * Patients with impaired consciousness or those judged to lack the capacity to provide informed consent
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Pusan National University Yangsan Hospital
Yangsan, Gyeongsangnam-do, 50612, South Korea
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