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Anesthesia may mess with your memory – new study investigates

NCT ID NCT05991817

Knowledge-focused Sponsor: University of Chile Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study at the University of Chile will test whether sevoflurane, a common general anesthetic, temporarily impairs spatial memory in 22 adults aged 30-50 undergoing elective gallbladder surgery. Participants will complete a virtual maze test and provide blood samples before and after surgery to measure memory changes and inflammation markers. The goal is to better understand how anesthesia affects the brain, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
sevoflurane
What this could lead to
If it works, this could help doctors understand how anesthesia affects memory, potentially leading to ways to prevent memory problems after surgery.
What could go wrong
This is a very small observational study (22 people) that only looks at short-term memory effects. It cannot prove cause and effect, and results may not apply to all surgeries or patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 22 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2023

Expected to finish

Dec 2025

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients bewteen 30 and 50 years old who will undergo to an elective laparoscopic surgery of cholecystectomy.

Ages

30 to 50 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Candidate for elective laparoscopic surgery of cholecystectomy. * Age 30 to 50 years. Exclusion Criteria: * Visual or hearing difficulties. * Malignant hyperthermia. * Being treated with centrally acting drugs, such as anxiolytics, antidepressants, antipsychotics, anticonvulsants, anticholinergics, and first-generation antihistamines. * Present a disorder of the sphere of neuropsychiatry * Substance abuse disorder.

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Conditions

The condition(s) this trial relates to.

Memory Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Spatial memory disorder

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Centro de Investigación Cínica Avanzada (CICA), Hospital Clinico de la Universidad de Chile

    RECRUITING

    Santiago, RM, 7690306, Chile

  • Hospital Clinico de la Universidad de Chile

    RECRUITING

    Santiago, RM, 7690306, Chile