Can kitchen oils beat chemo side effects? new study tests sesame oil and aloe vera
NCT ID NCT07346677
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares three topical treatments—sesame oil, aloe vera gel, and nitroglycerin ointment—against no treatment for preventing phlebitis (vein inflammation) caused by chemotherapy. Researchers will enroll 190 adults with breast or colon cancer receiving specific chemo drugs through a peripheral IV. The goal is to see which, if any, reduces the severity of phlebitis.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- sesame oil, aloe vera gel, nitroglycerin ointment
- What this could lead to
- If effective, these simple topical treatments could help prevent painful vein inflammation during chemotherapy, improving patient comfort.
- What could go wrong
- This is a small, early-phase trial that has not yet started. The treatments may not work better than no intervention, and results may not apply to all chemotherapy types.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 190 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * adult conscious patients of both gender. * Patients receiving chemotherapy antimetabolites (5-fluorouracil). * Patients receiving chemotherapy alkylating agents (Cisplatin). * Patients receiving chemotherapy through peripheral IV cannula. * Patients breast cancer colon cancer. Exclusion Criteria: * Phlebitis has already appeared at the IV infusion site. * Patients using port or central venous catheters to administer chemotherapy. - Patient radiation therapy, immunity therapy and palliative therapy * Patients receiving chemotherapy (antitumor antibiotics, plant alkaloids).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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