Does a serrated nose bone predict sinus trouble? CT scans may tell
NCT ID NCT07739927
First seen Jul 31, 2026 · Last updated Jul 31, 2026
Summary
This study looks at whether a rare, jagged shape of a small bone inside the nose (the inferior turbinate) is linked to thickening of the lining in the nearby maxillary sinus. Researchers will review existing cone-beam CT scans from adults aged 18-75 to compare sinus and nasal features between sides with and without this variation. The goal is to better understand the significance of this anatomical variation and improve how such findings are reported.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If a link is found, it could improve how doctors read sinus scans and spot related sinus issues earlier.
- What could go wrong
- This is an observational imaging study, so it can only show associations, not cause and effect. The findings may not apply to everyone.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 105 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will consist of adult individuals aged 18-75 years who underwent cone-beam computed tomography (CBCT) imaging for routine diagnostic purposes at Recep Tayyip Erdoğan University, Faculty of Dentistry, Department of Oral and Maxillofacial Radiology between January 2025 and June 2026. Existing CBCT images from the institutional radiology archive will be retrospectively reviewed. The study population will include individuals whose CBCT images provide adequate visualization of the maxillary sinuses, nasal cavity, ostiomeatal complex, and inferior turbinates for evaluation of sinonasal anatomical structures. Patients with craniofacial anomalies, maxillofacial trauma, previous sinonasal surgery, pathological conditions affecting the evaluated anatomical structures, or CBCT images unsuitable for accurate assessment will be excluded. The study aims to evaluate the relationship between serrated inferior turbinate variation, maxillary sinus mucosal thickness, and other sin
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Individuals aged 18-75 years. * Patients who underwent cone-beam computed tomography (CBCT) imaging for routine diagnostic purposes between January 2025 and June 2026. * CBCT images including both maxillary sinuses, nasal cavity, ostiomeatal complex, and inferior turbinates. * CBCT images with sufficient diagnostic quality and clearly visible anatomical boundaries for evaluation and measurements. * CBCT images in which the anatomical landmarks required for nasal septal deviation angle measurement (crista galli, maxillary spine, and the most deviated point of the nasal septum) can be clearly identified. Exclusion Criteria: * Patients with maxillofacial trauma, fractures, or conditions affecting the midface anatomy. * Patients with congenital craniofacial anomalies (e.g., cleft lip and palate) or syndromes affecting facial anatomy. * Patients with a history of sinonasal, inferior turbinate, or maxillary sinus surgery. * CBCT images with insufficient diagnostic quality, motion artifacts, or metal artifacts preventing accurate evaluation. * Patients with pathological lesions affecting the maxillary sinus or nasal cavity anatomy, including cysts, tumors, or aggressive inflammatory lesions. * CBCT findings suggestive of fungal sinusitis, including heterogeneous hyperdense contents, calcifications, bone expansion, or invasive changes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
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How to take part
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The official record
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