New study tests best emergency treatment for deadly sepsis shock
NCT ID NCT04569942
First seen Nov 21, 2025 · Last updated May 18, 2026 · Updated 25 times
Summary
This study looks at 1000 adults with septic shock (a severe infection causing very low blood pressure) in emergency departments. It compares two approaches: giving less IV fluid and starting blood-pressure-raising drugs early, versus giving more fluid first and adding drugs later if needed. The goal is to see which method helps patients spend more days alive and out of the hospital within 90 days.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Alfred Hospital
Melbourne, Victoria, 3004, Australia
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Angliss Hospital
Ferntree Gully, Victoria, 3156, Australia
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Auckland City Hospital
Auckland, North Island, 1023, New Zealand
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Ballarat Base Hospital
Ballarat, Victoria, 3353, Australia
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Bankstown Hospital
Bankstown, New South Wales, 2200, Australia
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Barwon Health Geelong Hospital
Geelong, Victoria, 3220, Australia
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Bendigo Hospital
Bendigo, Victoria, 3550, Australia
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Box Hill Hospital
Box Hill, Victoria, 3128, Australia
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Bunbury Hospital
Bunbury, Western Australia, 6230, Australia
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Bundaberg Hospital
Bundaberg, Queensland, 4670, Australia
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Caboolture Hospital
Caboolture, Queensland, 4510, Australia
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Cairns Hospital
Cairns, Queensland, 4870, Australia
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Casey Hospital
Berwick, Victoria, 3806, Australia
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Dandenong Hospital
Dandenong, Victoria, Australia
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Dunedin Hospital
Dunedin, Otago, 9054, New Zealand
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Fiona Stanley Hospital
Perth, Western Australia, 6150, Australia
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Flinders Medical Centre
Streaky Bay, South Australia, 5025, Australia
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Gold Coast University Hospital
Southport, Queensland, 4215, Australia
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Hervey Bay Hospital
Hervey Bay, Queensland, 4655, Australia
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Ipswich Hospital
Ipswich, Queensland, 4305, Australia
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John Hunter Hospital
New Lambton Heights, New South Wales, 2305, Australia
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Mackay Base Hospital
Mackay, Queensland, 4740, Australia
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Maroondah Hospital
Ringwood East, Victoria, 3135, Australia
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Middlemore Hospital
Middlemore, Otahuhu, 1640, New Zealand
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Monash Medical Centre
Clayton, Victoria, 3168, Australia
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Nepean Hosital
Kingswood, New South Wales, 2747, Australia
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Northern Hospital
Epping, Victoria, 3076, Australia
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Port Macquarie Base Hospital
Port Macquarie, New South Wales, 2444, Australia
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QE II Jubilee Hospital
Brisbane, Queensland, 4108, Australia
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Robina Hospital
Robina, Queensland, 4226, Australia
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Royal Darwin & Palmerston Hospital
Darwin, Northern Territory, 0811, Australia
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Royal Melbourne Hospital
Parkville, Victoria, 3050, Australia
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Royal North Shore Hosptial
Sydney, New South Wales, 2065, Australia
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Royal Perth Hospital
Perth, Western Australia, 6000, Australia
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Royal Prince Alfred Hospital
Camperdown, New South Wales, 2050, Australia
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Ryde Hospital
Sydney, New South Wales, 2112, Australia
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St John of God Hospital
Midland, Western Australia, 6056, Australia
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St John of God Murdoch Hospital
Murdoch, Western Australia, 6150, Australia
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St. Vincent's Hospital
Fitzroy, Victoria, 3065, Australia
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St. Vincent's University Hospital
Elm Park, Dublin, D04 T6F4, Ireland
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Sunshine Coast university hospital
Sunshine Coast, Queensland, 4560, Australia
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Tamworth Hospital
Tamworth, New South Wales, 2340, Australia
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Taranki Hospital
Hawera, 4640, New Zealand
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The Prince Charles Hospital
Brisbane, Queensland, 4032, Australia
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The Queen Elizabeth Hospital
Adelaide, South Australia, 5011, Australia
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Toowoomba Hospital
Toowoomba, Queensland, 4350, Australia
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Townsville Hospital
Townsville, Queensland, 4810, Australia
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Wangaratta Hospital
Wangaratta, Victoria, 3677, Australia
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Wellington Hospital
Wellington, 2820, New Zealand
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Westmead Hospital
Westmead, New South Wales, 2145, Australia
Conditions
Explore the condition pages connected to this study.