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Blood tests may reveal who will develop deadly clotting disorder during sepsis

NCT ID NCT06986798

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 25 times

Summary

This study looked at 150 adults with sepsis in the ICU to find early warning signs in the blood that could predict a dangerous condition called DIC, where blood clots form throughout the body. Researchers checked for specific biomarkers and tracked patients for up to 56 days. No new treatments were given—only standard care. The goal was to better understand how sepsis leads to DIC, especially in European patients.

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Contacts and locations

Locations

  • AZ Groeninge - Campus Kennedylaan

    Kortrijk, 8500, Belgium

  • Azienda Ospedaliero-Universitaria Di Bologna IRCCS_Policlinico Sant'Orsola - Anestesia e TI Polivalente

    Bologna, 40138, Italy

  • Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo_Ospedale S. Carlo - Anestesia e Rianimazione

    Milan, 20153, Italy

  • CHRU de Tours - Hôpital Bretonneau - Médecine Intensive Réanimation

    Tours, Centre-Val de Loire, 37044, France

  • Centre Hospitalier Départemental Vendée - Service de réanimation polyvalente

    La Roche-sur-Yon, Pays de la Loire Region, 85000, France

  • Centre Hospitalier Universitaire (CHU) de Liege - Domaine Universitaire du Sart Tilman

    Liège, 4000, Belgium

  • Centre Hospitalier Universitaire d'Angers - Médecine Intensive Réanimation et Médecine Hyperbare

    Angers, Pays de la Loire Region, 49100, France

  • Centre Hospitalier Universitaire de Limoges Dupuytren 1 - Service de réanimation polyvalente

    Limoges, New Aquitaine, 87042, France

  • Clinique Saint-Pierre d'Ottignies - Intensive Care

    Ottignies-Louvain-la-Neuve, 1340, Belgium

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Anestesia, Rianimazione, Terapia Intensiva e Tossicologia Clinica

    Roma, 00168, Italy

  • Hopital Hotel Dieu Nantes - Service de Médecine Intensive Réanimation

    Nantes, Pays de la Loire Region, 44000, France

  • Hopitaux Universitaires de Strasbourg Nouvel Hopital Civil - Service de Médecine Intensive Réanimation

    Strasbourg, Grand Est, 67091, France

  • Hospital Clinico San Carlos | Unidad de Cuidados Intensivos

    Madrid, 28040, Spain

  • Hospital Universitari Vall D Hebron | Unidad de Cuidados Intensivos

    Barcelona, 08035, Spain

  • Hospital Universitario Central De Asturias | Unidad de Cuidados Intensivos

    Oviedo, Principality of Asturias, 33011, Spain

  • Hospital Universitario De Getafe | Unidad de Cuidados Intensivos

    Getafe, Madrid, 28905, Spain

  • Hospital Universitario Virgen Del Rocio S.L. | Unidad de Cuidados Intensivos

    Seville, 41013, Spain

  • Humanitas Mirasole S.p.A. - Anestesia e Terapie Intensive

    Rozzano, 20089, Italy

  • Hôpital Raymond-Poincaré - Service de Médecine Intensive - Réanimation, Médecine Hyperbare

    Garches, Île-de-France Region, 92380, France

  • Kliniken der Stadt Köln gGmbH - Krankenhaus Merheim - Lungenklinik

    Cologne, North Rhine-Westphalia, 51109, Germany

  • Klinikum der Universität München AöR - Klinik für Anaesthesiologie (Campus Großhadern)

    München, 81377, Germany

  • Maasstad

    Rotterdam, South Holland, 3079 DZ, Netherlands

  • MedUni Graz | Innere Medizin, ICU

    Graz, 8036, Austria

  • MedUni Innsbruck | Innere Medizin I, Internistische Intensiv- und Notfallmedizin

    Innsbruck, Tyrol, 6020, Austria

  • MedUni Wien | Univ. Klinik für Klinische Pharmakologie

    Vienna, 1090, Austria

  • Medisch Spectrum Twente - Intensive Care

    Enschede, Overijssel, 7512 KZ, Netherlands

  • RKH Klinikum Ludwigsburg

    Ludwigsburg, 71640, Germany

  • Universitaetsklinikum Carl Gustav Carus an der Technischen Universitaet Dresden | Medizinische Klinik I - FB Haemostaseologie

    Dresden, 01307, Germany

  • Universitaetsklinikum Essen | Klinik für Anaesthesiologie und Intensivmedizin

    Essen, 45147, Germany

  • Universitair Medisch Centrum St. Radboud

    Nijmegen, 6500HB, Netherlands

  • Universite Catholique de Louvain (UCL) - Cliniques Universitaires Saint-Luc

    Woluwe-Saint-Lambert, 1200, Belgium

Conditions

Explore the condition pages connected to this study.