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Brain's word web may predict alcohol relapse risk

NCT ID NCT05636033

Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how alcohol use disorder (AUD) might reorganize the way the brain links words and ideas. Researchers will compare 30 AUD patients and 30 healthy controls using word-association tasks and brain tests. The goal is to see if these mental patterns can help predict who will relapse after quitting alcohol.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help identify mental patterns that predict relapse in people with alcohol use disorder, pointing toward new ways to support recovery.
What could go wrong
This is a small, early exploratory study with only 41 participants. It does not test a treatment, so any findings will need much more research before they can help patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

41 people

The number who actually took part.

Started

Apr 2023

Finished

Oct 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Two groups of participants will be included in this study. The first one consists of a pool of alcohol use disorder, the second one consists of a pool of healthy controls ; they will be matched as much as possible on age, gender, and educational level.

Ages

30 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: For alcohol use disorder patients * Severe alcohol use disorder * French as mother tongue * Right-hander * Patient abstinent from alcohol since 15 to 30 days at the inclusion * Patient free from benzodiazepine since at least 48hours at the inclusion * Patient who gave his informed written consent * Currently in outpatient or inpatient care For healthy controls * French as mother tongue * Right-hander * Participant who gave his informed written consent Exclusion Criteria: For alcohol use disorder patients * Patient under guardianship or under justice safeguard measures * Patient under measure of therapeutic injunction * Pregnancy or breastfeeding declared * Meeting Diagnostic and Statistical Manual 5 (DSM) criteria for substance use disorder other than Tobacco * Meeting DSM-5 criteria for non substance use disorder * Patient presenting severe or progressive disease that interfere with experimental tasks, such as neurological diseases (TBI, epilepsy, stoke) , hepatic diseases, cancer, HIV, Hepatitis C Virus (HCV), and unstable psychiatric comorbidities. For healthy controls * Participant under guardianship or under justice safeguard measures * Participant under measure of therapeutic injunction * Pregnancy or breastfeeding declared * Meeting DSM-5 criteria for alcohol use disorder * Meeting DSM-5 criteria for substance use disorder other than Tobacco * Meeting DSM-5 criteria for non substance use disorder * Currently under benzodiazepine * Participant presenting severe or progressive disease that interfere with experimental tasks, such as neurological diseases (TBI, epilepsy, stoke) , hepatic diseases, cancer, HIV, HCV, and unstable psychiatric comorbidities.

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Conditions

The condition(s) this trial relates to.

alcohol abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alcohol use disorder

Contacts and locations

Locations

  • Fernand Widal Hospital

    Paris, Île-de-France Region, 75010, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.