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Weight-Loss drug tested as surprise depression treatment

NCT ID NCT07136714

First seen Jan 10, 2026 · Last updated May 19, 2026 · Updated 20 times

Summary

This study tests whether semaglutide, a drug used for diabetes and weight loss, can improve mood in 116 people with major depression who are also overweight or obese. Participants will receive either semaglutide or a placebo once a week for 26 weeks, in addition to their usual depression medications. The main goal is to see if depressive symptoms decrease more with semaglutide than with placebo.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mental Health Centre North Zealand

    RECRUITING

    Hillerød, Denmark, 3400, Denmark

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.