First chinese trial tests drug for rare genetic nerve tumors

This early-phase study is testing the safety and effects of the drug selumetinib in Chinese children and adults with Neurofibromatosis Type 1 (NF1) who have inoperable nerve tumors called plexiform neurofibromas. About 32 participants will take the oral medication twice daily until their disease worsens or side effects become too severe. The main goals are to understand how the body processes the drug and to monitor for any safety issues, while also checking if the tumors shrink.