New drug shrinks thyroid tumors before surgery in early trial
NCT ID NCT04759911
First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 26 times
Summary
This study tests whether giving the drug selpercatinib before surgery can shrink thyroid cancers that have a specific genetic change (RET alteration). About 30 people with advanced or recurrent thyroid cancer will take selpercatinib for a short time before their operation. The goal is to make surgery easier and more effective, helping to control the disease long-term.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287, United States
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
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University of Michigan Health Systems
Ann Arbor, Michigan, 48109, United States
Conditions
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