Which therapy wins for low Self-Esteem? new study pits COMET against CBT
NCT ID NCT06101810
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two talking therapies—COMET and CBT—to see which one better improves self-esteem in people with various mental health issues. About 70 participants will be randomly assigned to one of the two treatments. Researchers will measure changes in self-esteem, anxiety, depression, and overall mental health at the end of treatment and again six months later.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2023
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: \- A self-perceived low self-esteem established by both patient and caregiver by means of (consent to) referral for self-esteem treatment. Exclusion Criteria: * severe suicidality for which hospitalization or other forms of crisis care is necessary, * acute psychosis, * current manic episode, * current alcohol or drug abuse, * insufficient knowledge of the Dutch language, * illiteracy * being unable to identify at least one positive aspect of oneself, which does not need to be felt as convincing for the participant. The latter is an excluding criterium formulated by the COMET protocol.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Stichting GGZ Noord-Holland-Noord
RECRUITINGHeerhugowaard, North Holland, 1703WC, Netherlands
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