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Next-Gen mRNA flu shot passes first safety test in humans

NCT ID NCT06125691

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 29 times

Summary

This early-stage study tested a new type of seasonal flu vaccine called ARCT-2138, which uses self-amplifying mRNA technology to potentially boost immune responses. Researchers gave the vaccine to 139 healthy adults aged 18-49 and 65-85 to check for side effects and measure antibody levels. The goal was to find the safest and most effective dose before moving to larger trials.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Emeritus Research Camberwell

    Melbourne, Victoria, 3124, Australia

  • Nucleus Network Brisbane Clinic

    Brisbane, Queensland, Australia

Conditions

Explore the condition pages connected to this study.