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Large study aims to pinpoint cancer return rates and swelling risks after treatment

NCT ID NCT04291612

First seen Oct 31, 2025 · Last updated Jun 23, 2026 · Updated 33 times

Summary

This study is observing about 1,715 people with early-stage endometrial cancer to see how often the cancer comes back and how often lymphedema (swelling) happens after standard treatment. Participants will have regular check-ups for 36 months. The goal is to gather real-world data to improve future care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • ADVENTHEALTH (Data collection only)

    RECRUITING

    Orlando, Florida, 32804, United States

    Contact Phone: •••-•••-••••

  • Charles University and General University Hospital (Data Collection Only)

    TERMINATED

    Prague, Czechia

  • FONDAZIONE POLICLINICOUNIVERSITARIO A. GEMELLI, ITALY (Data Collection Only)

    NOT_YET_RECRUITING

    Roma, Italy

    Contact Phone: •••-•••-••••

  • Hartford Healthcare Cancer Institute @ Hartford Hospital

    RECRUITING

    Hartford, Connecticut, 06102, United States

    Contact Phone: •••-•••-••••

  • L'Azienda Sanitaria Universitaria Friuli Centrale

    RECRUITING

    Udine, Italy

    Contact Email: •••••@•••••

  • Lehigh Valley Health Network

    RECRUITING

    Allentown, Pennsylvania, 18103, United States

    Contact Phone: •••-•••-••••

  • Mayo Clinic (Data Collection and Data Analysis)

    ACTIVE_NOT_RECRUITING

    Rochester, Minnesota, 55905, United States

  • Memorial Sloan Kettering Basking Ridge (All protocol activities)

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Bergen (All protocol activities)

    RECRUITING

    Montvale, New Jersey, 07645, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Commack (All Protocol Activities)

    RECRUITING

    Commack, New York, 11725, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Monmouth (All protocol activities)

    RECRUITING

    Middletown, New Jersey, 07748, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Nassau (All protocol activities)

    RECRUITING

    Rockville Centre, New York, 11553, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Westchester (All protocol activities)

    RECRUITING

    Harrison, New York, 10604, United States

    Contact Phone: •••-•••-••••

  • Miami Cancer Institute Baptist Health South Florida

    RECRUITING

    Miami, Florida, 33143, United States

    Contact Phone: •••-•••-••••

  • OSLO UNIVERSITY HOSPITAL,RIKSHOPITALET (Data Collection Only)

    NOT_YET_RECRUITING

    Oslo, Norway

    Contact Phone: •••-•••-••••

  • OSPEDALE MICHELE E PIETRO (Data Collection Only)

    RECRUITING

    Ferrera, Italy

    Contact Phone: •••-•••-••••

  • UNIVERSITY OF MILANO-BICOCCA, ITALY (Data Collection)

    NOT_YET_RECRUITING

    Milan, Italy

    Contact Phone: •••-•••-••••

  • University of Miami (Data Collection Only)

    NOT_YET_RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this trial could provide clearer data on recurrence rates and lymphedema risks after standard endometrial cancer treatment, helping doctors and patients make more informed decisions.

What could go wrong

This is an observational study, not testing a new treatment. It cannot prove that any intervention works better than current care. Results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

Carcinoma, Endometrioid endometrium neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.