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Obesity drug trial participants tracked for a decade to see Long-Term health effects

NCT ID NCT04972721

Knowledge-focused Sponsor: Novo Nordisk A/S Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows people who were in the SELECT trial to see how their health changes over the next 10 years. No new medicine is given—participants just fill out a health questionnaire every 6 months. The goal is to learn about long-term effects like heart attacks, cancer, weight changes, and quality of life after stopping the study drug.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

3,439 people

The number who actually took part.

Started

Sep 2023

Finished

Aug 2025

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants of the SELECT trial (EX9536-4388 ) are invited to transition to SELECT-LIFE (follow-up study) when SELECT ends.

Ages

45 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Randomized into the SELECT clinical trial (EX9536-4388) and has not withdrawn consent, regardless of level of participation, dose achieved or treatment discontinuation. * Signed SELECT-LIFE consent obtained before any study-related activities (study-related activities are any procedure related to recording of data according to the protocol). Exclusion criteria: * Mental incapacity, unwillingness or language barriers precluding adequate understanding or cooperation

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity Overweight

Contacts and locations

Locations

  • AngioCor Blumenau

    Blumenau, Santa Catarina, 89020-430, Brazil

  • CIP Centro Integrado de Pesquisas do Hospital de Base

    São José do Rio Preto, São Paulo, 15090-000, Brazil

  • CPCLIN - Centro de Pesquisas Clínicas

    São Paulo, São Paulo, 01228-200, Brazil

  • CPQuali Pesquisa Clínica Ltda

    São Paulo, São Paulo, 01228-000, Brazil

  • Cárdio Pulmonar da Bahia

    Salvador, Estado de Bahia, 40170130, Brazil

  • Departamento de Gastroenterologia - HCFMUSP

    São Paulo, São Paulo, 05403-000, Brazil

  • Eurolatino Medical Research Center

    Uberlândia, Minas Gerais, 38400-500, Brazil

  • Hospital São Vicente de Paulo

    Passo Fundo, Rio Grande do Sul, 99010-080, Brazil

  • Hospital do Coração do Brasil

    Brasília, Federal District, 70390-700, Brazil

  • Instituto Brasil de Pesquisa Clinica

    Rio de Janeiro, 20241-180, Brazil

  • Instituto Dante Pazzanese de Cardiologia

    São Paulo, São Paulo, 04012-909, Brazil

  • Instituto de Pesquisa Clínica de Campinas

    Campinas, São Paulo, 13060-080, Brazil

  • Instituto do Coração - HCFMUSP

    São Paulo, São Paulo, 05403-000, Brazil

  • MAster Centre for Latvia

    Marupes, 2167, Latvia

  • Master Centre Netherlands

    Alphen aan den Rijn, 2408 AV, Netherlands

  • Master Centre for Algeria

    Algiers, 16035, Algeria

  • Master Centre for Argentina

    Prov. de Buenos Aires, B1636DSU, Argentina

  • Master Centre for Australia

    North Sydney, New South Wales, 2060, Australia

  • Master Centre for Brazil

    Säo Paulo, São Paulo, 05001-100, Brazil

  • Master Centre for Canada

    Mississauga, Ontario, L4W 4XI, Canada

  • Master Centre for Denmark

    Copenhagen S, 2300, Denmark

  • Master Centre for Finland

    Espoo, FI-02600, Finland

  • Master Centre for Germany PMS

    Mainz, 55124, Germany

  • Master Centre for Greece

    Vouliagment, 16671, Greece

  • Master Centre for Ireland

    Dublin, D09 X8W3, Ireland

  • Master Centre for Italy

    Rome, 00144, Italy

  • Master Centre for Japan

    Tokyo, 1000005, Japan

  • Master Centre for Malaysia

    Selangor Darul Ehsan, Malaysia

  • Master Centre for Norway

    Rud, 1309, Norway

  • Master Centre for South Africa

    Sandton, Gauteng, 2146, South Africa

  • Master Centre for Sweden

    Malmö, 202 15, Sweden

  • Master Centre for Tawain

    Taipei, 106, Taiwan

  • Master Centre for Thailand

    Bangkok, 10500, Thailand

  • Master Centre for USA

    Plainsboro, New Jersey, 08536, United States

  • Master Centre for United Kingdom

    Gatwick, West Sussex, RH6 0PA, United Kingdom

  • Master centre for India

    Bangalore, 560001, India

  • Novo Nordisk Croatia Ltd.

    Zagreb, 10 020, Croatia

  • Núcleo de Pesquisa Clínica S/S

    Curitiba, Paraná, 80730-150, Brazil

More trials for these conditions

Other studies related to the condition(s) this trial covers.