Stem cell secretions vs. PRP: which injection grows more hair?
NCT ID NCT07429253
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether injections of secretome (a substance made by stem cells) or platelet-rich plasma (PRP) can improve hair density and thickness in people with androgenetic alopecia (common baldness). Forty men and women with mild to moderate hair loss will receive injections every two weeks for eight weeks. The goal is to see which treatment works better for regrowing hair.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Secretome (stem cell byproducts) and Platelet-Rich Plasma (PRP) injections
- What this could lead to
- If it works, this could point toward a new, non-surgical treatment for common hair loss using stem cell secretions.
- What could go wrong
- This is a very small, early-phase trial (40 people) comparing two experimental injections. Results may not apply to everyone, and long-term safety or effectiveness is unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1/2
Runs two stages together: safety and dose first, then whether the treatment works.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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25 to 59 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male patients with androgenetic alopecia, aged 25 to 59 years, with clinical presentation consistent with Hamilton-Norwood grades II to VI, seeking treatment at the Dermatology and Venereology Outpatient Clinic of Prof. Dr. I.G.N.G. Ngoerah General Hospital. * Female patients with androgenetic alopecia, aged 25 to 59 years, with clinical presentation consistent with Ludwig grades I to III, seeking treatment at the Dermatology and Venereology Outpatient Clinic of Prof. Dr. I.G.N.G. Ngoerah General Hospital. * Female patients who are not currently pregnant or breastfeeding. * Patients who have discontinued anti-androgen medication and minoxidil for at least 1 month prior to the procedure. * Patients with no known allergies to secretome components and/or materials used in the platelet-rich plasma (PRP) preparation process. * Patients who are proficient in Indonesian and willing to provide written informed consent. Exclusion Criteria: * Participants who are unable to speak or understand Indonesian and/or are unwilling to provide written informed consent. * Patients presenting with types of hair loss other than androgenetic alopecia. * Patients currently undergoing therapy with 5-alpha reductase inhibitors. * Patients who have received intradermal corticosteroid injections to the scalp within at least 6 months prior to the study. * Patients with active infections and/or active dermatitis on the scalp. * Patients with a known history of allergy to secretome components and/or materials used in the platelet-rich plasma (PRP) preparation process. * History of hypertrophic scarring or blood clotting (coagulation) disorders. * Patients unable to complete the research procedures in their entirety.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Prof. dr. I.G.N.G. Ngoerah Central General Hospital
RECRUITINGDenpasar, Bali, 80113, Indonesia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a scalp gel turn back male pattern baldness?
- Can a Four-Times-a-Year injection regrow hair in men?
- Can exosome shots outperform minoxidil for baldness?
- Can tiny needles boost hair growth in balding men?
- A battle for your hair: herbal oil vs. minoxidil serum in a Head-to-Head trial
- Can light boost PRP's power against hair loss?