Could a second ejaculate boost IVF success? new trial investigates
NCT ID NCT07056400
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This study looks at whether using sperm from a second ejaculate (collected 1-2 hours after the first) can improve fertilization and embryo quality in ICSI, a type of IVF. Researchers will compare sperm quality and pregnancy outcomes between first and second ejaculates in 108 couples where the male partner has abnormal sperm. The goal is to see if this simple change can lead to better results.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Nour El-Hayat Fertility Center
Cairo, Cairo Governorate, 11762, Egypt
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could offer a simple, non-invasive way to improve ICSI outcomes for couples with male infertility.
What could go wrong
This is a small, early-stage trial with no phase designation. Results may not apply to all infertility cases, and the approach may not significantly improve pregnancy rates.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.