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Emergency rooms may become a frontline for HIV prevention in teens

NCT ID NCT07728123

Prevention Sponsor: Westat Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Aug 18, 2026 · Updated 3 times

Summary

This trial tests three ways to screen adolescents and young adults for HIV in emergency departments: targeted screening based on risk, universal opt-in screening offered to everyone, and universal opt-out screening where testing is done unless declined. The goal is to see which approach finds more HIV cases and gets more young people started on prevention (PrEP) or treatment quickly. Digital health tools help identify and link eligible teens to care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
HIV screening strategies (targeted, universal opt-in, universal opt-out) delivered via digital health
What this could lead to
If successful, this could identify the most effective way to screen teens for HIV in emergency departments and quickly connect them to prevention or treatment.
What could go wrong
The trial compares different screening approaches, but real-world adoption may face barriers. Results depend on how well digital tools engage adolescents.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 84,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Oct 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

14 to 24 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 14-24 years, inclusive * Present to the participating ED, regardless of chief complaint during the study period Exclusion Criteria: * None

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Conditions

The condition(s) this trial relates to.

Emergencies HIV infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV infections

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    5 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Baylor College of Medicine

    RECRUITING

    Houston, Texas, 77030, United States

  • Emory Atlanta Adolescent Consortium

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Johns Hopkins University

    RECRUITING

    Baltimore, Maryland, 21287, United States

  • St. Jude Children's Research Hospital

    RECRUITING

    Memphis, Tennessee, 38015, United States

  • University of South Florida

    RECRUITING

    Tampa, Florida, 33612, United States

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