Emergency rooms may become a frontline for HIV prevention in teens

NCT ID NCT07728123

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial tests three ways to screen adolescents and young adults for HIV in emergency departments: targeted screening based on risk, universal opt-in screening offered to everyone, and universal opt-out screening where testing is done unless declined. The goal is to see which approach finds more HIV cases and gets more young people started on prevention (PrEP) or treatment quickly. Digital health tools help identify and link eligible teens to care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
HIV screening strategies (targeted, universal opt-in, universal opt-out) delivered via digital health
What this could lead to
If successful, this could identify the most effective way to screen teens for HIV in emergency departments and quickly connect them to prevention or treatment.
What could go wrong
The trial compares different screening approaches, but real-world adoption may face barriers. Results depend on how well digital tools engage adolescents.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baylor College of Medicine

    NOT_YET_RECRUITING

    Houston, Texas, 77030, United States

  • Emory Atlanta Adolescent Consortium

    NOT_YET_RECRUITING

    Atlanta, Georgia, 30322, United States

  • Johns Hopkins University

    NOT_YET_RECRUITING

    Baltimore, Maryland, 21287, United States

  • St. Jude Children's Research Hospital

    RECRUITING

    Memphis, Tennessee, 38015, United States

  • University of South Florida

    RECRUITING

    Tampa, Florida, 33612, United States

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