Could a device ease Post-Stroke pain without pills?
NCT ID NCT05563038
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a device called Scrambler Therapy to see if it can reduce pain after a stroke by at least 50%. Researchers will enroll 100 adults who have had a stroke and have ongoing pain. Participants will receive either 5 or 10 treatments, and the results will be compared to standard pain medications.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Scrambler Therapy (a device that delivers electrical stimulation to reduce pain)
- What this could lead to
- If successful, this could offer a non-drug option for people with persistent pain after a stroke.
- What could go wrong
- This is a small, early-stage study with only 100 participants, so results may not apply to everyone. The therapy may not work better than standard treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2023
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Men and women over the age of 18 with ischemic or hemorrhagic stroke seen on imaging and a positive finding for pain in the area(s) affected by their stroke location will be included. * The patients must be at least one month post-stroke but can otherwise enroll at any point. Exclusion Criteria: * Patients with TIA * Patients with no evidence of stroke on MRI * Patients with implantable devices such as pacemakers, defibrillators, spinal cord stimulators * Patients with history of myocardial infarction in the past 6 months * Patients with uncontrolled epilepsy * Patients with symptomatic brain metastases
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Johns Hopkins Bayview Hospital
RECRUITINGBaltimore, Maryland, 21224, United States
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