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New ultrasound test could spot sciatica faster

NCT ID NCT07136441

Diagnosis Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study tests a new way to measure sciatic nerve stiffness using ultrasound (shear wave elastography) during leg movements. Researchers will compare 30 people with low back pain and sciatica to 30 healthy volunteers. The goal is to see if nerve stiffness differs between the groups and between two movement sequences, which could help diagnose sciatica more accurately.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a better, non-invasive way to diagnose sciatica and guide treatment for low back pain patients.
What could go wrong
This is a small, early-stage study (60 participants) that only measures nerve stiffness, not treatment outcomes. Results may not apply to all patients or lead to immediate clinical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Feb 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Sixty subjects of both genders will be participated in this study. Their age will range between 25 to 40 years. They will receive verbal and written explanations for this study. If they decide to participate in this study, they will sign the consent form. The sample will be selected from the faculty of physical therapy outpatient clinics and at El kasr Elainy.

Ages

25 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Thirty participants ranging in age from 25 to 40 years from both genders with a diagnosis of low back pain with radiating leg pain and thirty control group. * The main symptoms are low back pain with unilateral leg pain(sciatica) for 3-12 months for group A. * Patients with lumbar disc herniation (L4-5) with diagnostic imaging as MRI for group A. * Positive straight leg raising are considered for inclusion in the study for group A. * Control group must be free from any symptoms of nerve irritation or compression, with normal neurological examination findings, including reflexes, sensation, negative straight leg raising and motor strength. Exclusion Criteria: * Diabetes mellitus. * Any type of polyneuropathy * Trauma of lumbar spine * Previous history of back surgery * Piriformis syndrome. * Participants with conditions that reduce image quality on US imaging (thick gluteal subcutaneous fat tissue. * Hip joint prosthesis. * Professional athletes (Neto et al., 2024). * Skin infection

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Conditions

The condition(s) this trial relates to.

lumbar disk herniation, susceptibility to sciatic neuropathy sciatica

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Sciatic nerve

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Cairo University

    RECRUITING

    Giza, Egypt

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