Knee block mystery: does numbing agent reach the sciatic nerve?
NCT ID NCT07301476
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at why a numbing injection in the thigh (adductor canal block) works so well for knee surgery pain. Researchers think the medicine may spread to the sciatic nerve, but they want to measure how often this happens. About 70 adults having knee surgery will be tested for numbness and muscle strength one and four hours after the block. The goal is to better understand the block's pain-relieving effects, not to test a new treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will be all the consecutive patients scheduled for elective knee surgery under general anesthesia in our center and receiving an adductor canal block.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * patients over 18 years old scheduled for elective knee surgery under general anesthesia * in our center * receiving an adductor canal block Exclusion Criteria: * patients cognitively impaired, * patients suffering from peripheral neuropathy at the lower limb, * patients receiving an IPACK block or surgical knee infiltration to complete the adductor canal block analgesia. * patients who refused to take part in this study * pregnant or breastfeeding patients * patients under guardianship * imprisoned patients, * patients without any medical insurance
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department of Anesthésia, CHU Raymond Poincaré - APHP
RECRUITINGBoulogne-Billancourt, 92100, France
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