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Brain scans reveal how positive thinking may change choices in schizophrenia

NCT ID NCT06745479

First seen Mar 14, 2026 · Last updated Jun 23, 2026 · Updated 19 times

Summary

This study looks at how attention and thinking strategies influence decision-making and brain activity in people with schizophrenia or schizoaffective disorder compared to healthy volunteers. Participants will use a positive thinking strategy during a gambling task while having their brains scanned with MRI. They will also answer short surveys about their daily activities and feelings for one week. The goal is to understand how brain function during decision-making relates to real-world choices.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Center for Advanced Human Brain Imaging Research

    RECRUITING

    Piscataway, New Jersey, 08854, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Emotional Regulation Psychotic Disorders schizoaffective disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.